eTRANSAFE is proud to partner up with NC3Rs in their recently announced CRACK IT challenge for a virtual second species.

The aim of the Challenge is to apply advanced computational and mathematical modelling approaches to develop a suite of models that will ultimately replace the use of the dog in six to nine-month (chronic) toxicology studies for new drug development programs.

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Important advances of the eTRANSAFE project were shared during the 12th Consortium Meeting held from June 17 to 18, 2021. Over 2 days, the members of the project spoke about the work carried out since the last meeting with encouraging results.

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The technology multinational GMV joined the eTRANSAFE consortium in June 2020

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Historical control databases are established by many companies (i) enabling contextualization of results from single studies against previous studies performed under similar conditions, (ii) to properly design studies and/or (iii) to come up with quality control instruments. Although the use of historical control data in supporting inferences varies across different assays; one major opportunity is the derivation of so-called Virtual Control Groups (VCGs) for replacement of animals in the control groups and thus enabling a 3R strategy for future animal testing approaches.

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The virtual 11th CM was held on 16 and 17 of February 2021

The eTRANSAFE consortium gathered for the 11th time to assess and discuss recent project developments as well as short-term plans until the next assembly scheduled in June.

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