Towards a Quantum Leap in Drug Safety Assessment – eTRANSAFE hosts its closing event with the participation of external experts

Towards a Quantum Leap in Drug Safety Assessment – eTRANSAFE hosts its closing event with the participation of external experts

The 17th and final eTRANSAFE Consortium Meeting took place in Sitges, Barcelona on 22-24 of February 2023. The event was open to the wider scientific community, bringing together over 100 participants to celebrate the results of what has been more than five years of successful collaboration.

In addition to showcasing the final outputs of the project through short presentations, demos and use cases, the event was also attended by international keynote speakers. In the course of three days, we had the pleasure of hearing from these external experts on topics such as the use of artificial intelligence in drug and chemical safety, promotion of animal-free research, uses and challenges of data sharing and the role of public-private partnerships in promoting drug safety evaluations.

The main achievement of eTRANSAFE is the revolutionary ToxHub platform. ToxHub brings together preclinical and clinical databases in an integrative data infrastructure, combined with innovative computational and visualisation tools that aim to radically improve the predictivity, feasibility and reliability of translational safety assessment during the drug development process. 

Ensuring post-project sustainability is key for conserving and continuing project assets and often presents important challenges for consortia. eTRANSAFE has been successful in promoting continuity for ToxHub, and the plan is for it to evolve and grow in the hands of the company Instem, as the future holder of the platform. Instem representatives presented their ambitious roadmap for the platform during the meeting. To address the challenges Public-Private Partnerships often face in terms of sustainability, the meeting also featured a roundtable discussion led by sustainability experts. The roundtable highlighted experiences and learnings from eTRANSAFE and the related initiatives VHP4Safety, BigPicture, TransQST & TransBioLine, whose representatives were invited to join the event.

The meeting finalized with the 3rd Edition of the eTRANSAFE Awards, granted to consortium members who have made outstanding contributions to the project. The Award for Outstanding Individual Academic Contribution went to Javier Corvi (BSC) and the Award for Outstanding Individual Industry Contribution to Inari Soininen (Synapse). This edition also featured Special Jury Awards granted to Annika Kreuchwig (Bayer), Philip Drew (PDS), Rowan Parry (EMC), Alexander Amberg (Sanofi) and Katharine Briggs (Lhasa). We send our most heartily congratulations to all the winners and thank them for their excellent contributions to the project!

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