The eTRANSAFE (Enhancing TRANslational SAFEty Assessment through Integrative Knowledge Management) project works to improve the efficiency of translational safety assessment approaches during the medicines discovery pipeline

Virtual Control Groups: one step forward into the future of animal testing in toxicology

Historical control databases are established by many companies (i) enabling contextualization of results from single studies against previous studies performed under similar conditions, (ii) to properly design studies and/or (iii) to come up with quality control instruments. Although the use of historical control data in supporting inferences varies across different assays; one major opportunity is the derivation of so-called Virtual Control Groups (VCGs) for replacement of animals in the control groups and thus enabling a 3R strategy for future animal testing approaches.

eTRANSAFE 11th Consortium Meeting

The virtual 11th CM was held on 16 and 17 of February 2021

The eTRANSAFE consortium gathered for the 11th time to assess and discuss recent project developments as well as short-term plans until the next assembly scheduled in June.


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